Bisphenol A levels in human urine.

Bisphenol A levels in human urine.

The estrogenic effects of bisphenol A (BPA) have been reported in human cells (E-screen assays) and in (italic)in vivo(/italic) studies of rodents, although the latter reports remain controversial, as do the exposure levels and adverse health effects of BPA in humans. In this study we report on an analytical high-performance liquid chromatography/fluorescence method for BPA and its conjugate in...

Measurement of Bisphenol-A in Human Urine by Ultra-Performance Liquid Chromatography/Tandem Mass Spectrometry

A simple and rapid ultra-performance liquid chromatographic tandem mass spectrometric assay for the measurement of bisphenol-A (BPA) in human urine was developed and validated. Sample preparation involved addition of 4-nitrophenol (as an internal standard, IS) to 1.0 ml human urine sample containing BPA, and extraction with ethyl acetate and hexane (6:4,v:v), evaporation, and dissolving the res...

Altered Testicular Histomorphometric and Antioxidant Levels Following in vivo Bisphenol-A Administration

Background: Bisphenol-A (BPA) is a pervasive environmental toxin that is used in the production processes of many consumables and equipment that are in daily application. The aim of this study was to determine the effects of BPA on the structural and functional integrity of the reproductive system in male Wistar rats and its interaction with melatonin. Methods: Adult female rats in pro-estrus ...

Human Excretion of Bisphenol A: Blood, Urine, and Sweat (BUS) Study

BACKGROUND Bisphenol A (BPA) is an ubiquitous chemical contaminant that has recently been associated with adverse effects on human health. There is incomplete understanding of BPA toxicokinetics, and there are no established interventions to eliminate this compound from the human body. Using 20 study participants, this study was designed to assess the relative concentration of BPA in three body...

Organic pollutants in urine 2014 and levels of bisphenol A 2009 and 2014 in the adult population of Northern Sweden